Nanocomposit coating to enable point-of-care testing of dopamine
It is very important to develop point-of-care (POC) testing method of dopamine (DA) in human tissue to help the diagnosis and treatment of the diseases such as Parkinson and Depression. Fortunately, carbon nanotechnology offers an opportunity to solve this problem. Now, graphene nanoplate/carbon nanotubes (GNP/CNT) nanocomposite screen-printed electrodes (SPE) have been developed with a unique waterborne carbon nanocoating technology.
POC testing strategy
The resulting GNP/CNT SPE has a linear DA detection range from 0.4 μM to 40 μM with differential pulse voltammetry (DPV) method, with an excellent anti-interference to the ascorbic acid (AA) and urea (UA). As a result, DA in human serum can be measured with POC testing strategy.
The study has been published in Progress in Organic Coatings, Volume 170, September 2022.