Double benefit for medical devices

A new study presents a chitosan coating fabricated through nanotopography and alkylation for the prevention of bacterial attachment and corrosion on medical devices.

Medical equipment in close-up.
The chitosan coating slowed down the corrosion of carbon steel.  Image source: noac - Pixabay (symbol image).

Although metallic materials are widely used in biomedical devices, most of them have no antibacterial property and exhibit corrosion-related problems in physiological environments. A new study aimed to develop a biocide-free chitosan coating to inhibit bacterial adhesion and corrosion. First, a chitosan coating fabricated through nanotopography was formed on the surface of carbon steel by using soft imprinting technology. Next, hexanal was grafted onto the chitosan. Finally, the surface hydrophobic properties, antibacterial adhesion, and electrochemical corrosion resistance of chitosan coatings with and without nanopatterning and hexanal grafting were investigated.

Improved corrosion resistance

The results indicated that the hydrophobic angle of chitosan with both nanopatterning and hexanal grafting exceeded 120° and that the hysteresis angle was only 20°, which may help inhibit the attachment of Staphylococcus aureus and Escherichia coli. During an electrochemical corrosion test, chitosan with both nanopatterning and hexanal grafting exhibited the highest corrosion potential and the lowest corrosion current density, indicating improved corrosion resistance. These results suggest that imparting nanopatterning and alkylation properties to chitosan solves not only the problem of bacterial attachment to bare metal substrates but also the problem of corrosion.

The study has been published in Progress in Organic Coatings, Volume 174, January 2023.

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