The researchers tested biocompatible polymer coatings with adapted degradability for medical applications. Source: sasint / Pixabay.
31. Jul 2019 | Application Areas
Degradable polymeric composite coatings for biodegradable medical applications
A current study deals with degradable polymeric composite coatings for biodegradable medical applications deposited by laser technology.
Scientist report on the bio-polymeric composite coatings deposition for medical applications, demanding adjustable biodegradability, by the Matrix Assisted Pulsed Laser Evaporation, a sterile laser tool technology, tested for degradation, wettability and bio-compatibility preservation.
The specific FTIR bands of both materials indicated stoichiometric deposition of composite coatings, and meanwhile suggested the predominant presence of amorphous SF phase, as also validated by XRD, with low intensity maxima emerging from the amorphous matrix. Concerning the PSADT component, XRD clearly evidenced its specific crystalline contribution.
Slower degradation tendency
The degradation behaviour in simulated body fluid at 37 °C in dynamic regime was studied as first step of applicability in potential sustained controlled release applications (and/or degradable implanted electronics). Weighing measurements of degraded samples confirmed slower degradation tendency with increasing initial PSADT amount. They also revealed approximately zero order SBF-degradation for 1:1 SF-PSADT ratio. The in vitro assays showed uniform spreading of human mesenchymal stem cells on all synthesised coatings.
The study is published in: Progress in Organic Coatings Volume 134, September 2019, Pages 11-21.
Resins for Water-borne Coatings
Expand your knowledge and get fully acquainted with the various aspects of water-borne coatings - from production to properties to special features of their use! With the slow change from solvent-borne resins and coatings to water-borne coatings "Resins for waterborne coatings" is a must-read for any formulator wanting to expand their knowledge. The authors discuss important aspects of the "solvent-to-water-transition" of the past 40 to 50 years, take a deep dive into the key aspects and theories behind the production, properties and applications of these resins as well as providing an overview of how they are currently used in water-borne coatings.
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