12. Jul 2021 | Application Areas
Antibacterial hybrid coatings
Lysostaphin enzyme is an effective antibacterial agent proven to be promising for the prevention of healthcare-associated infections related to methicillin-resistant Staphylococcus aureus (MRSA). Recently, safe, and non-toxic antibacterial hybrid coatings consisting of lysostaphin and waterborne polyurethane (PU) have been presented.
Lysostaphin was covalently immobilised onto polydopamine functionalised halloysite nanotubes (HNTs) to obtain stable HNT-lysostaphin nanohybrid structures with high effective lysostaphin concentrations, which were then incorporated into PU coatings.
Easily applied to surfaces in healthcare facilities
The resulting PU/HNT-lysostaphin hybrid coatings presented strong antibacterial activity against S. aureus with a >99 % killing efficiency. The incorporation of lysostaphin into the polymer matrix via HNTs as a carrier enhanced the stability of the enzyme resulting in non-leaching coatings that presented high operational stability over multiple bacterial incubation cycles and high storage stability without any significant loss of enzymatic activity. Furthermore, PU/HNT-lysostaphin coatings demonstrated significant antibiofilm properties and reduced the formation of S. aureus biofilms by 70 % relative to neat PU coatings.
According to the researchers, the lysostaphin based antibacterial hybrid coatings developed in the study, which can be easily applied to surfaces in healthcare facilities and medical devices offer an effective approach for the prevention of S. aureus associated nosocomial infections.
The study has been published in Progress in Organic Coatings, Volume 156, July 2021.
Additives for Water-borne Coatings
Water-borne systems are the coatings of the future. The market is developing an insatiable appetite for ecologically sound coatings based on renewable raw materials. The demands on coating performance are at least as high as those on environmental compatibility. Additives help to protect the environment by effectively reducing the use of organic solvents. Many of today’s water-borne coatings could not be formulated without them. When incorporated into water-borne paints, coatings and printing inks, they enhance both the production process and the performance of the applied inks and coating materials. Additives for water-borne coatings is a must read for formulators wishing to brush up on water-borne coating systems, as well as experts seeking to have detailed knowledge at their finger tips.
You are currently not logged in
To leave a comment, please log in.
There was an error while sending your comment. Please try again.
Your comment was too long. There are a maximum of 2048 symbols allowed!