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Wednesday, 03 June 2020
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Raw materials & technologies, Technologies, Functional coatings

Nanostructured antimicrobial coatings

Tuesday, 29 September 2009

Polyurethanes having co-polyoxetane soft blocks form antimicrobial layer.

Researchers found out about antimicrobial properties.

Researchers found out about antimicrobial properties.

Researchers from Virginia Commonwealth University, USA, released a study about antimicrobial properties of polyurethanes. Polyoxetanes are polyethers or formally 2,2’-substituted-1,3-propylene oxides. Co-polyoxetane telechelics 1 may be represented as P(AB), where A and B are repeat units with differing side chains. These telechelics are incorporated into polyurethanes and used as polymer surface modifiers. As an example, polyurethanes were prepared with P(AB) soft blocks where A = a fluorous "chaperone" or PEG-like side chain and B = alkylammonium side chains. At 2 wt % in a conventional polyurethane, two of the surface modifiers effect 100 % kill of a 107 CFU/ml aerosol challenge of Gram +/- pathogenic bacteria in 30 min. The effectiveness of the new modifiers is due in part to surface nano-topology and spatial distribution of alkylammonium groups mimicking naturally occurring biocidal peptides such as the magainins and cecropins.

related links:

http://www.vcu.edu/

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