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Sunday, 27 September 2020
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Raw materials & technologies, Raw materials, Coatings additives

"Promising natural biocides for coatings"

Thursday, 23 July 2009

Natural biocides for coatings, like antimicrobial peptides (AMPs), show promising results in the lab.

Dr. Steve McDaniel, Managing partner and Chief Innovation Officer at ReactiveSurfaces Source: ReactiveSurfaces

Dr. Steve McDaniel, Managing partner and Chief Innovation Officer at ReactiveSurfaces Source: ReactiveSurfaces

The ecotrend approaches the biocide technology. How they obtain conventional biocides explains Dr. Steve McDaniel, Managing partner and Chief Innovation Officer at ReactiveSurfaces. 1. The Biocidal Products Directive requires that biocidal products containing active substances to be authorized or registered. You are showcasing non-toxic and non polluting biocides. How do these green biocides work? Pharmaceutical research has lead to promising natural biocides for coatings, antimicrobial peptides (AMPs). AMPs act through by an initial peptide-cell membrane interaction followed by displacement of lipids and alteration of the membrane structure. By compromising the integrity of the membrane, in addition to rapid killing, AMPs in small amounts have a synergistic effects on other biocides. This mode of action prevents resistance development. 2. How do this bioenineerd biocides perform in comparision to conventional biocides? Efficacy studies comparing AMPs to traditional biocides show that these bio-based additives work as well and, in many cases, better than conventional biocides, at very low concentrations. For instance, AMPs admixed into 2-part polyurethane films on metal coupons out perform quaternary silanes and nano-silver biocides by 4-5 logs against bacteria. 3. What are the potential applications? AMPs combine human-safety and environmentally-friendly nature of naturally-derived biocides with the fast-acting and broad spectrum nature of more traditional chemical biocides. They can be used alone or synergistically in combination with existing biocides to quickly and effectively kill fungi and bacteria, including the spore stages of such microorganisms, as well as certain protozoa and encapsulated viruses.

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