Characterization of microgels

Microgels are particles of cross-linked polymer networks dispersed in a medium, such as water. These polymers, which range from 100 nm to 1 µm in diameter, can undergo rapid, reversible and dramatic phase transitions when triggered by slight environmental variations in temperature, pH or ionic strength. Medical applications for smart polymers range from diagnosis to intelligent distribution of drugs and actuators (such as artificial muscles and valves), while other sectors are benefiting from new technologies for microelectronic sensors and environmentally adaptive clothing. The Zetasizer Nano series from Malvern Instruments enables the study of very small, weakly scattering particles such as polymers at low concentrations. Its novel arrangement of optics maximises detection of scattered light while maintaining signal quality. The wide range of sample properties available for measurement with the system include, particle size, molecular weight, and zeta potential.